Proton Therapy

Proton therapy delivers focused radiation using protons instead of X-rays. 

Proton Therapy for Prostate Cancer

Proton therapy is one of several ways to deliver radiation for prostate cancer. While it offers a different method of delivery, current research shows that photon-based therapies like IMRT and SBRT remain the most established and widely used treatments with similar outcomes.

What Is Proton Therapy?

Proton therapy uses positively charged particles (protons) to treat cancer. Protons release their energy at a specific depth in the body, known as the Bragg peak, allowing for precise targeting of the tumor. The goal is to reduce radiation beyond the prostate.

Photon Therapy: IMRT and SBRT

Photon therapies such as IMRT (Intensity-Modulated Radiation Therapy) and SBRT (Stereotactic Body Radiotherapy) use X-rays to treat prostate cancer. These techniques have been refined over decades and are backed by strong long-term data.

  • IMRT: Delivers small doses of radiation over many sessions, shaping the beam to match the prostate.
  • SBRT: Uses fewer sessions with higher doses and pinpoint accuracy.

Both IMRT and SBRT are widely available, effective, and well-studied, with excellent outcomes and manageable side effects.

What the Research Shows

Recent studies comparing proton therapy with IMRT have found:

  • No significant difference in prostate cancer control between the two approaches.
  • Similar outcomes in quality of life, including urinary, bowel, and sexual health.

This means that while proton therapy is safe, it does not offer a clear advantage over photon therapy for most patients.

Considerations for Proton Therapy

Proton therapy is:

  • Available at select specialized centers
  • Often more expensive and less accessible
  • Not proven to be superior in treating low- or intermediate-risk prostate cancer compared to photon therapy

Is Photon Therapy Still the Best Choice?

For most men with low- or intermediate-risk prostate cancer, photon-based treatments like IMRT and SBRT provide:

  • Proven, long-term success
  • Broad availability in community and academic settings
  • Comparable or better insurance coverage

Your doctor can help you choose the best treatment based on your diagnosis, goals, and access to care. For most patients, photon therapy remains the most practical, evidence-supported option for effective prostate cancer treatment.

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