Tissue Biopsy

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Tissue Biopsy for Diagnosis

When prostate cancer is suspected, a tissue biopsy is one of the most important steps in confirming the diagnosis. A biopsy involves removing small samples of tissue from the prostate to check for cancer under a microscope. This webpage will explain what a prostate biopsy is, how MRI-guided biopsies work, and other important information to help you understand the process.

What is a prostate biopsy?

A prostate biopsy is a procedure where a doctor removes small pieces of tissue from the prostate gland. These samples are sent to a lab, where a pathologist looks for cancer cells. This is the most reliable way to diagnose prostate cancer.

How is Prostate biopsy Done?

The most common type of biopsy is a transrectal ultrasound (TRUS)-guided biopsy. Here’s how it works:
A small ultrasound probe is inserted into the rectum to create images of the prostate.

Using these images, the doctor guides a thin needle into the prostate to take tissue samples.

What is an MRI guided biopsy?

An MRI-guided biopsy uses advanced imaging to target suspicious areas in the prostate more accurately. This method is often recommended if:
1) Your PSA levels are high but a previous biopsy was negative.
2) An MRI scan shows areas that look abnormal.

MRI-guided biopsies are especially helpful for finding cancer in hard-to-reach areas of the prostate or for detecting small tumors that might be missed with standard techniques.

When is a biopsy Done?

A biopsy is typically recommended if:
1) Your PSA levels are higher than normal.
2) Your doctor feels a lump or hard area during a Digital Rectal Exam (DRE).
3) An imaging test, like an MRI, shows something suspicious.

After the biopsy, the samples are examined by a pathologist. The results usually include:

  • Whether cancer is present or not.
  • The Gleason Score, which measures how aggressive the cancer is.
  • Whether the cancer is localized or spreading to nearby areas.

What are the risks of Prostate biopsy

While prostate biopsies are generally safe, there are some risks, including:
1) Blood in your urine, semen, or stool (usually temporary).
2) Infection, which may require antibiotics.
3) Discomfort or mild pain in the area.

A prostate biopsy is a key tool for diagnosing prostate cancer and planning treatment. Advanced techniques like MRI-guided biopsies can improve accuracy and help target suspicious areas. If your doctor recommends a biopsy, ask questions and discuss any concerns you have. Understanding the process can help you feel more confident about your care.

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